Okay. After a REALLY successful 2-day session (by 'success' I mean I managed to get to lv4 in one take, with 70% health and NO POT USAGE, and then I only died twenty times to that huge lump of meat with claws), I'm seeing two things regarding inventory view that could, maybe, get improved:
1. ESC key does not take you out of Inventory menu or loot menu - not a big deal, but if you take into consideration that I key is a bit far from WSAD, not to mention even farther from Tab which initiates combat mode, in a crucial moment - say, a hostile zombie runs out of nowhere and hits you from behind while you're examining his dead buddy with tough leather boots - it may mean a difference between successful defense and having to scream in frustration, then explain to people in your household why the screaming, THEN re-rolling another character.
Solution: just bind ESC to make inventory, item and loot windows disappear when hit. If it's possible, it would help and trust me, if you use left hand for WSAD-ing, you would notice the difference.
2. Loot window opens up in the middle of the screen - this one's tied to the previous problem. Imagine that you have won a fight with TWO enemies, not one, but two! And one of them has a rusty shortsword, O Joy! In all that excitement, looking at the middle of the screen at your new not-so-shiny weapon, you forget that doors are open, the third member of that merry undead band is charging at you... oh look, he just entered into the blind zone, behind the open inventory window - you are now hitting I, then Tab quickly, but it's too late. Bye bye 50% health.
Now, before you go "that's what barricading is for" or "be prepared" or "always keep one eye open", I did all that. And still, you would be surprised how often mobs can sneak up on you when you honestly believe it's a safe moment to start digging for loot. Having a huge object that blocks your view in the center of the screen is crucial for abysmal failure in this game.
Solution: remember how neatly docked to left your own inventory is? Devs, put a smile on our faces and do the same with loot/item/chest windows. And, if multiple windows are open, there surely is a solution to stack them diagonally, to left and down, but also on the far right side of the screen... thus making a huge empty space, with your char centered and fully aware of his/her surrounding.